Association of Salivary Helicobacter pylori Infection with Oral Diseases: a Cross-sectional Study in a Chinese Population

نویسندگان

  • Yi-Jian Ding
  • Tian-Lian Yan
  • Xin-Lan Hu
  • Jian-Hua Liu
  • Chao-Hui Yu
  • You-Ming Li
  • Qun-Yan Wang
چکیده

OBJECTIVE The aim of this study was to detect the prevalence of oral H.pylori among adults and to investigate the correlation between H.pylori infection and common oral diseases. STUDY DESIGN A cross-sectional study was performed among adults Chinese who took their annual oral healthy examination at The First Affiliated Hospital, Zhejiang University School of Medicine, China. RESULTS The study included 1050 subjects in total and oral H.pylori infection occurred in 60.29% of the subjects. The prevalence rates of oral H.pylori in patients with periodontal diseases (63.42%) and caries (66.91%) were significantly increased than those without oral diseases (54.07%), respectively (P < 0.05), while the difference between subjects with recurrent aphthous stomatitis and controls was not significant. In addition, the differences of positive rates of H.pylori with or without history of gastric ulcer were statistically significant (69.47% vs 58.26%, P<0.05). Presenting with periodontal diseases (OR 1.473;95% CI 1.021 to 2.124), caries (OR 1.717; 1.127 to 2.618), and having history of gastric ulcer (OR 1.631; 1.164 to 2.285) increased the risk of H.pylori infection. CONCLUSIONS Oral H.pylori infection is common in adult Chinese, which is significantly associated with oral diseases including periodontal diseases and caries.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Molecular Detection of Oral Helicobacter pylori and Its Association with Dental Conditions Among Patients with Helicobacter Infection in Baghdad City

Background and Objective: Helicobacter pylori (H. pylori) is a bacterium known for its presence in the stomach, but it can also colonize the oral cavity and contribute to various oral and gastric diseases. This study aimed to detect the presence of oral H. pylori and investigate its potential association with dental caries and dental erosion. Methods: Saliva and plaque samples were collected f...

متن کامل

Association of Helicobacter pylori infection with serum vitamin B12 level in women of gestational age in Khorram Abad

Background: Helicobacter pylori (HP) infection is one of the most important causes of gastrointestinal diseases such as peptic ulcer. This bacterium has recently been reported to be associated with low serum vitamin B12 level. In this study we investigated the relationship between Helicobacter pylori seropositivity and the serum B12 level in women aging 15-49 years in Khorram Abad . Material...

متن کامل

Association of Myeloperoxidase -463 G/A Polymorphism with Clinical Outcome of Helicobacter Pylori infection in Iranian Patients with Gastrointestinal Diseases

Background: Polymorphisms in the immune related genes are important in the clinical outcome of Helicobacter pylori infection. Myeloperoxidase -463 G/A polymorphism has been shown to reduce enzyme expression and activity. Objective: the aim of the present study is to investigate the association of myeloperoxidase G-463A polymor-phism with clinical outcome of Helicobacter pylori infection. Method...

متن کامل

The possible role of dental plaque as extra-gastric reservoir of Helicobacter pylori in gastric re-infection: A science-metric study

BACKGROUND AND AIM: Helicobacter pylori (H. pylori) infection is one of the most common infections which still affects individuals worldwide. The main route for transmission of H. pylori infection is the oral route and this microorganism has been detected in dental plaque. In past decades, there have been a number of controversies about the station of dental pl...

متن کامل

Prevalence of Helicobacter Pylori Infection in Asymptomatic Children in Birjand, Eastern Iran

Background: Helicobacter pylori is the cause of serious diseases including gastric cancer and gastric mucosa–associated lymphoid tissue lymphoma.50% of world population is infected by this microorganism and it -based on epidemiologic studies - is mainly acquired during childhood . there is not enough evidence about prevalence of this infection in children and its risk factors so encourage us to...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2015